| Abstract: | 2-Hydroxyethyl methacrylate (0·01mol) was allowed to react with 0·01mol of hexamethylene di-isocyanate and the product was coupled to 0·01mol of β-cyclodextrin to form a new cyclodextrin-based copolymer. The interaction of the polymer with different steroids was investigated and the extent of adsorption was in the order cholesterol>progesterone>testosterone. The results indicate that the new polymer matrix could be used for the removal of steroids, particularly cholesterol, from a given medium. The polymer could also be used for sample purification, such as the removal of progesterone from a mixture prior to its analysis by other analytical techniques. The preliminary results show that the polymer may have interesting clinical and analytical applications. © of SCI. |
