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The Role of Psychobiotics in Supporting the Treatment of Disturbances in the Functioning of the Nervous System—A Systematic Review
Authors:Krzysztof Skowron  Anna Budzy&#x;ska  Natalia Wiktorczyk-Kapischke  Karolina Chomacka  Katarzyna Grudlewska-Buda  Monika Wilk  Ewa Wa&#x;ecka-Zacharska  Ma&#x;gorzata Andrzejewska  Eugenia Gospodarek-Komkowska
Abstract:Stress and anxiety are common phenomena that contribute to many nervous system dysfunctions. More and more research has been focusing on the importance of the gut–brain axis in the course and treatment of many diseases, including nervous system disorders. This review aims to present current knowledge on the influence of psychobiotics on the gut–brain axis based on selected diseases, i.e., Alzheimer’s disease, Parkinson’s disease, depression, and autism spectrum disorders. Analyses of the available research results have shown that selected probiotic bacteria affect the gut–brain axis in healthy people and people with selected diseases. Furthermore, supplementation with probiotic bacteria can decrease depressive symptoms. There is no doubt that proper supplementation improves the well-being of patients. Therefore, it can be concluded that the intestinal microbiota play a relevant role in disorders of the nervous system. The microbiota–gut–brain axis may represent a new target in the prevention and treatment of neuropsychiatric disorders. However, this topic needs more research. Such research could help find effective treatments via the modulation of the intestinal microbiome.
Keywords:psychobiotics  gut–  brain axis  microbiome  probiotics  nervous system diseases  neurodegenerative diseases  depression  autism spectrum disorders  Alzheimer’  s disease  Parkinson’  s disease
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