高血压的药物治疗进展

高血压病是临床上常见心血管疾病。中国高血压防治指南、国际高血压学会全球高血压实践指南，世界卫生组织成人高血压药物治疗指南等相继发布，对于指导高血压临床用药发挥了重要作用。钙通道阻滞剂（calcium channel blockers, CCB），血管紧张素转化酶抑制剂（angiotensin-converting enzyme inhibitors, ACEI）、血管紧张素受体拮抗剂（angiotensin receptor blockers, ARBs）、血管紧张素受体脑啡肽酶抑制剂（angiotensin receptor neprilysin inhibitor, ARNI）、噻嗪类利尿剂和β-受体阻滞剂等6类是目前临床上常用的降压药物。高血压药物控制的目标、高血压药物的应用时机、联合用药方案的选择，以及高血压合并其他疾病的药物选择，妊娠期高血压的用药，这些问题均是临床医生需要掌握的问题。

Progress of hypertension pharmacological treatment

Hypertension is a common cardiovascular disease. Chinese guidelines for the management of hypertension, the global practice guidelines for hypertension of the International Hypertension Society (ISH) and the guidelines for the treatment of adult hypertension drugs of the World Health Organization have been issued successively, which play an important role in guiding the clinical medication of hypertension. Calcium channel blockers (CCB), angiotensin converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARBs), angiotensin receptor neprilysin inhibitor (ARNI), thiazide diuretics and β-receptor blockers are commonly used in clinical antihypertensive drugs. The goal of hypertension drug control, the application timing of hypertension drugs, the selection of combined medication scheme, the drug selection of hypertension complicated with other diseases, and the medication of gestational hypertension are all problems that clinicians need to master.