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Caffeine Inhibition of Sterigmatocystin, Citrinin, and Patulin Production
Authors:ROBERT L. BUCHANAN  MOLLY A. HARRY  MICHAEL A. GEALT
Affiliation:Author Buchanan is affiliated with the USDA-ARS, Eastern Regional Research Center, 600 E. Mermaid Lane, Philadelphia, PA 19118. Author Harry is affiliated with the Dept. of Nutrition &Food Sciences, and Author Gealt is with the Dept. of Biological Sciences, Drexel Univ., Philadelphia, PA 19104.
Abstract:Microbiological medium was used to study the effect of caffeine on sterigmatocystin, citrinin, and patulin production by Aspergillus versicolor, Penicillium citrinum, and Penicillium urticae, respectively. Caffeine inhibited the growth of the three fungal species and decreased sterigmatocystin and patulin production. The effect on citrinin production appeared to be limited to a delay in toxin synthesis. A preliminary examination of P. urticae suggested that caffeine's anti-mycotoxigenic activity does not involve a generalized inhibition of lipid synthesis.
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