小型质谱双线形离子阱间离子传输

多级质谱串联在各个领域都有广泛应用。双线形离子阱的小型质谱可以实现类似传统三重四极杆质谱仪的串联质谱分析功能，而在此过程中，双阱间的离子传输为重要的仪器功能。在已发表的双线形离子阱工作中，对阱间离子传输，尤其是质量选择性传输鲜有系统的研究。本工作研究了离子阱q值、阱内气压、辅助性交流电（AC）的强度、辅助性AC的作用时长等因素对传输的目标离子强度的影响，优化了离子传输条件，如q1=q2=0.3，阱内气压为0.37 Pa，AC强度为350 mV，离子传输时长大于10 ms等。该结果对小型质谱双线形离子阱的自主研发和提升阱间离子传输效率具有指导作用。

Ion Transfer between Dual Linear Ion Traps (LITs) in a Miniature Mass Spectrometer

Tandem mass spectrometry(MS^n) is widely used in a variety of applications. Miniature mass spectrometers with dual linear ion traps(LITs) can achieve MS^n analysis similar to traditional lab-scale triple quadrupole mass spectrometers. The ion transfer between the two LITs plays an important role in the MS^n analysis process. In current works on dual-LIT mass spectrometry systems, ion transfer between the two LITs, especially in a mass-selective mode, has rarely been systematically studied. Here, the influence of several factors on the target ion transfer was studied, including the q value for both LITs, the pressure in the LITs, the amplitude of the auxiliary Alternating Current(AC), the duration of the auxiliary AC, etc. It was found that the optimized ion transfer condition was achieved under conditions including q1=q2=0.3, pressure at 0.37 Pa, AC amplitude of 350 mV and a transfer time longer than 10 ms. This result can be a reference for future development of hybrid mass spectrometers using dual-LIT configurations and for enhanced ion transfer efficiency between the two LITs.