| 芦荟粗多糖和芦荟苷对急性酒精中毒小鼠的解酒作用 |
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| 引用本文： | 叶青,汪何雅,钱和.芦荟粗多糖和芦荟苷对急性酒精中毒小鼠的解酒作用[J].食品工业科技,2012,33(13):355-358. |
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| 作者姓名： | 叶青 汪何雅 钱和 |
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| 作者单位： | 江南大学食品科学与技术国家重点实验室,江南大学食品学院,江苏无锡214122 |
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| 基金项目： | 区域特产资源生态高值利用技术研究与产品开发(2011BAZ02169) |
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| 摘 要： | 目的:通过建立急性酒精中毒小鼠模型来研究芦荟粗多糖和芦荟苷对于急性酒精中毒小鼠的解酒作用。结果表明:芦荟粗多糖(AP)和芦荟苷(Aloin)可以延长小鼠的醉酒潜伏期,缩短睡眠时间和醒酒时间。AP实验组的乙醇吸收最高峰在120min左右出现,与对照组相比,AP(9mg/kg·bw)组小鼠血液乙醇浓度缩小了25.49%;Aloin组的乙醇吸收最高峰在120～180min出现,Aloin(200mg/kg·bw)组乙醇浓度缩小了42.56%。因此,芦荟苷和芦荟粗多糖都对急性酒精中毒小鼠具有明显的解酒作用,能够显著降低小鼠血液乙醇浓度。
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| 关 键 词： | 芦荟粗多糖 芦荟苷 急性酒精中毒 解酒 |
Protective effects of crude aloe polysaccharides and aloin on mice with acute liver injury induced by alcohol |
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| YE Qing,WANG He-ya,QIAN He.Protective effects of crude aloe polysaccharides and aloin on mice with acute liver injury induced by alcohol[J].Science and Technology of Food Industry,2012,33(13):355-358. |
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| Authors: | YE Qing WANG He-ya QIAN He |
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| Affiliation: | *(State Key Laboratory of Food Science and Technology,School of Food Science and Technology,Jiangnan University,Wuxi 214122,China) |
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| Abstract: | The protective effects of crude aloe polysaccharides(AP) and aloin on acute ethanol-administrated mice were studied.The results showed that AP and aloin significantly prolonged drunk incubation period,decreased sleeping time and waking time of mice.The peak of ethanol concentration in plasm of AP administrated group appeared at about 120min after ethonal intake,and in the low dosage group(9mg/kg·bw),the peak appeared 25.49% less than the control group.The ethanol concentration peak of aloin administrated groups appeared around 120～180min and the peak of high dosage group(200mg/kg·bw) appeared 42.56% less than the control group.The results demonstrated that aloin and AP can effectively alleviated hangover and decreased alcohol content of plasma in acute ethanol-administrated mice. |
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| Keywords: | crude aloe polysaccharides aloin acute liver injury sober-up effect |
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