| 基于青霉胺自组装膜的生物传感器及其应用研究 |
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| 引用本文： | 牛凌梅,康维钧,马莉,薛鹏.基于青霉胺自组装膜的生物传感器及其应用研究[J].化学传感器,2008,28(3):33-38. |
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| 作者姓名： | 牛凌梅 康维钧 马莉 薛鹏 |
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| 作者单位： | 河北医科大学公共卫生学院,河北石家庄,050017;河北医科大学公共卫生学院,河北石家庄,050017;河北医科大学公共卫生学院,河北石家庄,050017;河北医科大学公共卫生学院,河北石家庄,050017 |
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| 摘 要： | 研究了青霉胺自组装膜在金电极上的电化学特性.在pH7.3的磷酸缓冲溶液中,利用差分脉冲法考察了多巴胺与尿酸在此修饰电极上的电化学行为.该电极可用于多巴胺与尿酸的同时测定,两者在修饰电极上的电位差可达到380 mV,且互不干扰.多巴胺与尿酸的氧化峰电流分别在1.0×10-4至1.0×10-3 mol/L,8.0×10-4至4.0×10-3 mol/L范围内与其浓度的大小呈良好的线性关系,检出限分别为6.5×10-6,2.1×10-5 mol/L.青霉胺自组装电极稳定性好,选择性高,可用于实际样品的测定,结果满意.
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| 关 键 词： | 青霉胺 自组装膜电极 多巴胺 尿酸 |
Study of biosensor and its application based on the penicillamine self-assembled monolayer |
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| Niu Ling-mei,Kang Wei-jun,Ma Li,Xue Peng.Study of biosensor and its application based on the penicillamine self-assembled monolayer[J].Chemical Sensors,2008,28(3):33-38. |
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| Authors: | Niu Ling-mei Kang Wei-jun Ma Li Xue Peng |
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| Affiliation: | Niu Ling-mei,Kang Wei-jun,Ma Li,Xue Peng (School of Public Health,Hebei Medical University,Shijiazhuang 050017,China) |
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| Abstract: | The fabrication and electrochemical characteristics of a penicillamine (PCA) self- assembled monolayer modified gold electrode were investigated. The electrochemical reactions of dopamine (DA) and uric acid (UA) at the penicillamine (PCA) electrode were studied by differential pulse voltammetry (DPV) in phosphate buffer of pH7.3. The PCA self- assembled electrode was used to the simultaneous electrochemical detection of them and the signals were well separated with a potential difference of over 380 mV and ... |
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| Keywords: | penicillamine self- assembled monolayer dopamine uric acid |
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