| 25MeV／u ^40Ar^14＋辐照肝癌细胞的生物学效应 |
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| 引用本文： | 周光明,高清祥.25MeV／u ^40Ar^14＋辐照肝癌细胞的生物学效应[J].辐射研究与辐射工艺学报,1997,15(3):171-174. |
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| 作者姓名： | 周光明 高清祥 |
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| 作者单位： | [1]中国科学院近代物理研究所 [2]兰州大学生物系 |
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| 基金项目： | “九五”重大课题“攀登计划B”项目 |
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| 摘 要： | 讨论了２５ＭｅＶ／ｕ ＾４０Ａｒ＾１４＋对培养的肝癌细胞ＳＭＭＣ－７７２１的生物学效应。结果表明：辐照后的癌细胞中出现多种染色体畸变类型，微核率比对照高得多，肝癌细胞的辐射受损程度与剂量呈正相关性，分次照射时，修复机制被逐渐激活，等剂量辐照的细胞损伤程度随辐照次数的增加而减轻。
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| 关 键 词： | 氩离子 生物辐射效应 肝癌细胞 放射治疗 |
THE BIOLOGICAL EFFECTS OF SMMC 7721 IRRADIATED BY 25MeV/u 40 Ar 14+ |
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| Zhou Guangming,Chen Weiqiang,Li Wenjian,Xie Hongmei,Dang Bingrong,Li Qiang,Han Guangwu,Huang Tao,Wei Zengquan.THE BIOLOGICAL EFFECTS OF SMMC 7721 IRRADIATED BY 25MeV/u 40 Ar 14+[J].Journal of Radiation Research and Radiation Processing,1997,15(3):171-174. |
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| Authors: | Zhou Guangming Chen Weiqiang Li Wenjian Xie Hongmei Dang Bingrong Li Qiang Han Guangwu Huang Tao Wei Zengquan |
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| Abstract: | The biological effects of SMMC 7721 irradiated by25MeV/u 40 Ar 14+ are studied The following results are obtained: (1)Various chromosomal aberrations are induced and the micronucleus frequency is higher than that of corresponding control (2) The greater the dose is,the heavier the cells are damaged (3) The repair system of cells is actived during fractionation irradiation and the efficiency of repair is enhanced responding to the irradiation times |
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| Keywords: | Argon ion SMMC 7721 Micronucleus frequency Biological radiation effects |
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