Monodisperse droplets by impinging flow-focusing |
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| Authors: | Tao Wu Zhaofeng Luo Weiping Ding Zhengdong Cheng Liqun He |
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| Affiliation: | 1.Department of Thermal Science and Energy Engineering,University of Science and Technology of China,Hefei,China;2.Biological and Life Sciences Division, Hefei National Laboratory of Physics Sciences at the Microscale,University of Science and Technology of China,Hefei,China;3.Center for Biomedical Engineering,University of Science and Technology of China,Hefei,China;4.Artie McFerrin Department of Chemical Engineering,Texas A&M University,College Station,USA |
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| Abstract: | We proposed a new flow-focusing technique for generation of monodisperse femtoliter droplets, based on the capillary micro-cross. A funnel-shaped interface of two phase system is observed in a capillary cross for mass production of uniform drops, where a tapered exit orifice is extruded into the dispersed feeding capillary. The droplets, down to 2 μm in size at frequency of 20 kHz, are controllable in size when choosing orifice and capillary sizes, as well as flow rates of inner and outer fluids. For a specific diameter of exit orifice, there is a maximal flow rate of outer fluid, beyond which the interface will be penetrated. Until then, the interface is in steady state and all droplets are highly uniform (<3%), implicating an absolute instability in the whole process. |
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