| 4-氯丁酰氯的合成研究 |
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| 引用本文： | 牛宇岚,李敏,段海龙.4-氯丁酰氯的合成研究[J].精细化工中间体,2006,36(3):21-22. |
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| 作者姓名： | 牛宇岚 李敏 段海龙 |
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| 作者单位： | 中北大学分校,化学工程系,山西,太原,030008 |
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| 摘 要： | 以-γ丁内酯为原料、无水氯化锌作催化剂、氯化亚砜做氯化剂进行开环氯化合成4-氯丁酰氯。对该氯化反应原理进行了阐述,考察了影响反应的主要因素。优化工艺条件为:在55℃加热搅拌反应22h,催化剂用量3%～5%,收率82.7%。
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| 关 键 词： | -γ丁内酯 4-氯丁酰氯 氯化 |
| 文章编号： | 1009-9212(2006)03-0021-02 |
| 修稿时间： | 2006-01-13 |
Synthesis of 4-Chlorobutyryl Chloride |
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| NIU Yu-lan,LI Ming,DUAN Hai-long.Synthesis of 4-Chlorobutyryl Chloride[J].Fine Chemical Intermediates,2006,36(3):21-22. |
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| Authors: | NIU Yu-lan LI Ming DUAN Hai-long |
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| Affiliation: | Department of Chemical Engineering, College of NorthChina Institute of Technology, Taiyuan 030008, China |
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| Abstract: | The synthesis of 4-chlorobutyryl chloride was described using γ-butyroctone as material,anhydrous zinc chloride as the catalyst and thionyl chloride as chloridum.The reaction principle is expounded,and the main factors affecting the reaction are investigated.Optimal conditions were obtained as follow:reaction temperature is 55℃,reaction time 22 h and percent amount of catalyst 3%~5%.The yield of the product is 82.7% under the optimal conditions. |
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| Keywords: | γ-Butyroctone 4-Chlorobutyryl chloride Chlorination |
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