Effect of Aqueous Polyethylene Glycol on 1,3‐Dipolar Cycloaddition of Benzoylnitromethane/Ethyl 2‐Nitroacetate with Dipolarophiles: Green Synthesis of Isoxazoles and Isoxazolines期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Effect of Aqueous Polyethylene Glycol on 1,3‐Dipolar Cycloaddition of Benzoylnitromethane/Ethyl 2‐Nitroacetate with Dipolarophiles: Green Synthesis of Isoxazoles and Isoxazolines

Authors:	R. Gangadhara Chary,G. Rajeshwar Reddy,Y. S. S. Ganesh,K. Vara Prasad,Akula Raghunadh,T. Krishna,Soumita Mukherjee,Manojit Pal

Abstract:	A 1:1 mixture of water‐polyethylene glycol (PEG) facilitated the 1,3‐dipolar cycloaddition of benzoylnitromethane/ethyl 2‐nitroacetate with terminal alkynes or alkenes leading to isoxazoles or isoxazolines under green conditions. The methodology is free from the use of any base, catalyst, dehydrating agent or hazardous solvent.

Keywords:	cycloaddition isoxazoles isoxazolines PEG polyethylene glycol water