| 克雷伯氏菌微氧发酵生产1,3-丙二醇的研究 |
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| 引用本文： | 王剑锋,修志龙,刘海军,范圣第.克雷伯氏菌微氧发酵生产1,3-丙二醇的研究[J].现代化工,2001,21(5):28-31. |
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| 作者姓名： | 王剑锋 修志龙 刘海军 范圣第 |
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| 作者单位： | 1. 大连民族学院化工系,
2. 大连理工大学生物工程系, |
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| 基金项目： | 国家自然科学基金(No.29806002)和山东大学微生物国家重点实验室开放基金资助项目. |
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| 摘 要： | 对克雷伯氏菌在厌氧和通1.2L/min空气的条件下间歇连续发酵生产1,3-丙二醇进行了研究,在两种条件下1,3-丙二醇的转化率接近.在通空气的条件下细胞能够正常代谢,并获得较高菌体密度,但有氧发酵的生产强度高于厌氧发酵;甘油处于限制状态、稀释率为0.1h-1的连续发酵中,有氧发酵1,3-丙二醇的转化率和生产强度均高于厌氧发酵.
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| 关 键 词： | 1 3-丙二醇 甘油 微氧发酵 克雷伯氏菌 |
| 修稿时间： | 2001年1月19日 |
Study on microaerobic conversion of glycerin to 1,3-propanediol by Klebsielle pneumoniae |
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| WANG Jian feng ,XIU Zhi long ,LIU Hai jun ,FAN Sheng di.Study on microaerobic conversion of glycerin to 1,3-propanediol by Klebsielle pneumoniae[J].Modern Chemical Industry,2001,21(5):28-31. |
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| Authors: | WANG Jian feng XIU Zhi long LIU Hai jun FAN Sheng di |
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| Affiliation: | WANG Jian feng 1,XIU Zhi long 2,LIU Hai jun 2,FAN Sheng di 1 |
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| Abstract: | The conversion of glycerin to 1,3 propanediol (1,3 PD) by Klebsielle pneumoniae with batch and continuous fermentation processes under anaerobic and microaerobic conditions was studied.The 1,3 PD conversion rates of both processes approached to the same level,but the productivity of 1,3 PD under microaerobic condition was higher than that under anaerobic condition inasmuch as normal metabolism of cells.In the continuous culture at a dilution rate of 0.1 h -1 and glycerin limitation,both yield and productivity of 1,3 PD under microaerobic condition were higher than that under anaerobic condition. |
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| Keywords: | propanediol glycerin microaerobic fermentation Klebsielle pneumoniae |
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