Instrumentation and calibration protocol for imaging dynamic features in dense-scattering media by optical tomography |
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| Authors: | Schmitz C H Graber H L Luo H Arif I Hira J Pei Y Bluestone A Zhong S Andronica R Soller I Ramirez N Barbour S L Barbour R L |
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| Affiliation: | Downstate Medical Center, State University of New York, Box 25, 450 Clarkson Avenue, Brooklyn, New York 11203, USA. |
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| Abstract: | Instrumentation is described that is suitable for acquiring multisource, multidetector, time-series optical data at high sampling rates (up to 150 Hz) from tissues having arbitrary geometries. The design rationale, calibration protocol, and measured performance features are given for both a currently used, CCD-camera-based instrument and a new silicon-photodiode-based system under construction. Also shown are representative images that we reconstructed from data acquired in laboratory studies using the described CCD-based instrument. |
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