| T型分岔血管中直导管注射药液介入溶栓的数值研究 |
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| 引用本文： | 刘赵淼,马瑞艳,刘鑫,史艺.T型分岔血管中直导管注射药液介入溶栓的数值研究[J].北京工业大学学报,2011,37(3):448-454. |
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| 作者姓名： | 刘赵淼 马瑞艳 刘鑫 史艺 |
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| 作者单位： | 北京工业大学,机械工程与应用电子技术学院,北京,100124;中国医学科学院,阜外心血管医院,北京,100037 |
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| 基金项目： | 国家自然科学基金资助项目(10502002); 北京市中青年骨干教师计划项目; 高等学校博士点专项基金资助项目(200800231121) |
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| 摘 要： | 建立了三维T型分岔血管中直导管药液注射溶栓的几何模型,采用计算流体力学方法,对介入药液注射溶栓进行了数值模拟研究.通过对药液进入支血管(靶血管)利用的情况,找出导管注射端的最佳位置和药液所需要的最佳注射速度,并给出了最佳值.研究结果为血管介入治疗的进一步研究和临床实践提供了依据.
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| 关 键 词： | 血栓 介入溶栓 药物注射 |
Numerical Simulations of Interventional Thrombus Dissolution through Straight-Conduit Injection in T-Bifurcation Vessel |
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| LIU Zhao-miao,MA Rui-yan,LIU Xin,SHI Yi.Numerical Simulations of Interventional Thrombus Dissolution through Straight-Conduit Injection in T-Bifurcation Vessel[J].Journal of Beijing Polytechnic University,2011,37(3):448-454. |
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| Authors: | LIU Zhao-miao MA Rui-yan LIU Xin SHI Yi |
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| Affiliation: | LIU Zhao-miao1,MA Rui-yan1,LIU Xin1,SHI Yi2(1.College of Mechanical Engineering and Applied Electronics Technology,Beijing University of Technology,Beijing 100124,China,2.Fuwai Cardiovascular Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China) |
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| Abstract: | A three-dimension geometry model of T-bifurcation vessel is established so that injection thrombus dissolution is numerically simulated by using computational fluid dynamics.The usage of medicine in the branch vessel(object vessel) is compared and analyzed to find the appropriate injection position and velocity.Finally the appropriate range of injection position and velocity are required.The research provides numerical statistics and reference for further study and clinical practice of interventional therap... |
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| Keywords: | thrombus interventional therapy medicine injection |
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