| 高区域选择性合成3-（芳胺）-N,N-二甲基丙酰胺衍生物 |
| |
| 引用本文： | 谭良谋.高区域选择性合成3-（芳胺）-N,N-二甲基丙酰胺衍生物[J].广州化工,2014(19):58-60. |
| |
| 作者姓名： | 谭良谋 |
| |
| 作者单位： | 茂名石化实华股份有限公司,广东 茂名,525000 |
| |
| 摘 要： | 以N,N-二甲基丙烯酰胺和芳胺类化合物为原料,盐酸为促进体系,经过分子间的高区域选择性加成,成功地构建出了3-（芳胺）-N,N-二甲基丙酰胺衍生物。采用1H-NMR、13C-NMR和熔点对目标产物进行了表征。研究表明该方法具有原料便宜易得、原子经济、后处理操作简单和产品纯度高等优点,为3-（芳胺）-N,N-二甲基丙酰胺衍生物的高效、快速合成提供了一条可选的策略。
|
| 关 键 词： | 芳胺 N N-二甲基丙烯酰胺 区域选择性 分子间加成 |
Highly Regio-selective Synthetic Strategy for 3-(Arylamino)-N,N-dimethylpropanamide Derivatives |
| |
| TAN Liang-mou.Highly Regio-selective Synthetic Strategy for 3-(Arylamino)-N,N-dimethylpropanamide Derivatives[J].GuangZhou Chemical Industry and Technology,2014(19):58-60. |
| |
| Authors: | TAN Liang-mou |
| |
| Affiliation: | TAN Liang-mou;Maoming Petro-Chemical Shihua Co.,Ltd.; |
| |
| Abstract: | The highly regioselective intermolecular addition for the synthesis of 3 - （arylamino） - N, N - dimethylpropanamide derivatives from aromatic amines and N, N - dimethylacrylamide in the presence of hydrochloride （HC1） was introduced. The structures of product were confirmed by 1H -NMR, 13C -NMR and melting point. The results showed that this synthetic route had the advantages of easy - obtained raw materials, atom economy, simple work - up and high purity product, therefore, this strategy provided a alternative method for the high efficient, rapid synthesis of 3 - （arylamino） - N, N - dimethylpropanamides. |
| |
| Keywords: | aromatic amines N N-dimethylacrylamide regioselectivity intermolecular addition |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
