Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity |
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Authors: | Marilena Pariano,Stefania Pieroni,Antonella De Luca,Rossana G. Iannitti,Monica Borghi,Matteo Puccetti,Stefano Giovagnoli,Giorgia Renga,Fiorella D’ Onofrio,Marina M. Bellet,Claudia Stincardini,Maria Agnese Della-Fazia,Giuseppe Servillo,Frank L. van de Veerdonk,Claudio Costantini,Luigina Romani |
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Affiliation: | 1.Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy; (M.P.); (S.P.); (A.D.L.); (R.G.I.); (M.B.); (G.R.); (F.D.); (M.M.B.); (C.S.); (M.A.D.-F.); (G.S.); (C.C.);2.Department of Pharmaceutical Science, University of Perugia, 06132 Perugia, Italy; (M.P.); (S.G.);3.Department of Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands; |
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Abstract: | |
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Keywords: | NLRP3 inflammasome anakinra superoxide dismutase 2 oxidative stress cystic fibrosis chronic granulomatous disease |
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