| 紫外-可见分光光度法测定盐酸氟桂利嗪胶囊的含量 |
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| 引用本文： | 江月华,林红.紫外-可见分光光度法测定盐酸氟桂利嗪胶囊的含量[J].广东化工,2012,39(6):217+216-217,216. |
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| 作者姓名： | 江月华 林红 |
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| 作者单位： | 浙江万邦药业股份有限公司质量管理部,浙江温岭,317500 |
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| 摘 要： | 为了建立盐酸氟桂利嗪生产过程中的快速分析方法,采用紫外-分光光度法和高效液相色谱法对盐酸氟桂利嗪进行测定。对比结果表明,以盐酸为溶剂,选择253 nm为测定波长,在盐酸氟桂利嗪为7.488～17.472μg.mL-1的浓度范围内,紫外-分光光度法与高效液相色谱法具有很好的可靠性,可以作为生产过程质量控制的快速测定方法。
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| 关 键 词： | 盐酸氟桂利嗪 分光光度法 含量测定 |
Determinination of the Content of Flunarizine Hydrochloride Capsules by Spectrophotometry |
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| Jianɡ Yuehua,Lin Hong.Determinination of the Content of Flunarizine Hydrochloride Capsules by Spectrophotometry[J].Guangdong Chemical Industry,2012,39(6):217+216-217,216. |
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| Authors: | Jianɡ Yuehua Lin Hong |
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| Affiliation: | (Quality Management Department Zhejiang Wanbang Pharmaceutical Co.,Ltd.,Wenling 317500,China) |
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| Abstract: | In order to establish an accurate and speedy detection method for manufacture process of the flunarizine hydrochloride capsules,a spectrophotometry method was studied by comparing with HPLC method.The linear rang was 7.488～17.472 μg·mL-1 when hydrochloric acid was used as solvent,and 253 nm as detection wavelength.The results showed that the spectrophotometry method had high accurate same as HPLC,and could be used as speedy detection method. |
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| Keywords: | flunarizine hydrochloride capsules spectrophotometry content determinination |
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