An insight into the inhibitory activity of dihydromyricetin against Vibrio parahaemolyticus |
| |
| Affiliation: | 1. Research Laboratory, Nordland Hospital, Bodø, Norway;2. Institute of Clinical Medicine, University of Tromsø - The Arctic University of Norway, Tromsø, Norway;3. Faculty of Health Sciences, K.G. Jebsen TREC, University of Tromsø - The Arctic University of Norway, Tromsø, Norway;4. Department of Immunology, Oslo University Hospital, and K.G. Jebsen IRC, University of Oslo, Norway;5. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway;6. Department of Anesthesiology, Nordland Hospital and University of Nordland, Bodø, Norway;7. Department of Laboratory Medicine, Nordland Hospital, Bodø, Norway |
| |
| Abstract: | The objective of this study is to investigate the antibacterial activity of dihydromyricetin (DMY) against Vibrio parahaemolyticus. The dilution method indicated that the minimum inhibitory concentration (MIC) of DMY against V. parahaemolyticus was at 0.625 mg/mL. The inhibitory effects of DMY against V. parahaemolyticus was further studied by analyzing cell morphology, cell injury, cell permeability, cell surface hydrophobicity (CSH) and antibacterial rate. The results showed bacterium cells are completely inactivated in a higher concentration (10 MIC). DMY treatment also lead to an increase in cell membrane permeability, cell injury as well as CSH. A good correlation between antibacterial rate and CSH was also observed. These findings indicated DMY could be used as a new alternative natural antibacterial agent for control pathogen growth in aquatic food. |
| |
| Keywords: | DMY Morphology Membrane permeability Cell surface hydrophobicity |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
