| 植物花青素通过JNK信号通路抗肿瘤机制研究进展 |
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| 引用本文： | 郅琦,李福香,杨雅轩,田勇,唐宇,石芳,明建.植物花青素通过JNK信号通路抗肿瘤机制研究进展[J].食品与机械,2017,33(7):215-220. |
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| 作者姓名： | 郅琦 李福香 杨雅轩 田勇 唐宇 石芳 明建 |
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| 作者单位： | 西南大学食品科学学院，重庆 400715;西南大学食品科学学院，重庆 400715；重庆市特色食品工程技术研究中心，重庆 400715 |
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| 基金项目： | 重庆市社会民生科技创新专项(编号：cstc20l5stums-ztzx80006)；国家自然科学基金面上项目(编号：31471576)；重庆市特色食品工程技术研究中心能力提升项目(编号：cstc2014pt-gc8001) |
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| 摘 要： | 文章综述了JNK信号通路的组成及活化机制,总结了植物花青素通过该信号通路抑制乳腺癌、前列腺癌、肝癌等恶性肿瘤发生、增殖、侵袭和凋亡的能力,以期为植物花青素应用于功能食品和药品的开发提供依据。
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| 关 键 词： | 植物花青素 JNK 信号通路 抗肿瘤机制 |
Plant anthocyanin exert antitumor effect and mechanism of by JNK signaling pathway |
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| ZHIQi,LIFuxiang,YANGYaxuan,TIANYong,TANGYu,SHIFang,MINGJian.Plant anthocyanin exert antitumor effect and mechanism of by JNK signaling pathway[J].Food and Machinery,2017,33(7):215-220. |
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| Authors: | ZHIQi LIFuxiang YANGYaxuan TIANYong TANGYu SHIFang MINGJian |
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| Affiliation: | College of Food Science, Southwest University, Chongqing 400715, China; College of Food Science, Southwest University, Chongqing 400715, China; Chongqing Engineering Research Center of Special Foods, Chongqing 400715, China |
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| Abstract: | JNK signaling pathway plays an important role in the pathogenesis and development of tumor. In this study, the composition and activation mechanism of JNK signaling pathway was reviewed. Moreover, the ability of inhibiting the proliferation, invasion and apoptosis of breast cancer, prostate cancer, liver cancer, etc by plant anthocyanin was summarized, in order to provide a certain basis for the application of plant anthocyanins in developing clinical medicine and drugs. |
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| Keywords: | plant anthocyanins JNK signaling pathway antitumor |
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