Application of synthetic biology in manufacture of bio-based plastics |
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Authors: | Yanqin XU Xizhi YANG Ruoshi LUO Yuhong HUANG Feng HUO Dan WANG |
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Affiliation: | 1.National-Municipal Joint Engineering Laboratory for Chemical Process Intensification and Reaction, School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China;2.Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China |
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Abstract: | Synthetic biology is a new discipline that uses engineering ideas as a guide to transform and reconstruct natural biological genomes, synthesize new biological components, construct new metabolic routes, and produce novel products or obtain new phenotypes. Bio-based plastics are plastics produced under the action of microorganisms or the chemical reactions using natural materials as raw materials. The usage of synthetic biology to construct engineered strains to produce bio-based plastics has become a hot topic in academia and industry. This paper reviews the development of synthetic biology and important techniques in the field of synthetic biology, focusing on the research progress in the field of metabolic pathways and engineering optimization for the construction of bio-based plastic polymer monomers and derivatives such as polyhydroxyalkanoate, nylon, polylactic acid, and butylene glycol succinate using synthetic biological techniques. |
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Keywords: | synthetic biology bio-based plastics metabolic engineering nylon engineering strains |
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