| 猪皮明胶肽抗小鼠外周肌肉疲劳作用的研究 |
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| 引用本文： | 董文宾,张小强,张闽.猪皮明胶肽抗小鼠外周肌肉疲劳作用的研究[J].西北轻工业学院学报,2012(5):77-81. |
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| 作者姓名： | 董文宾 张小强 张闽 |
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| 作者单位： | 陕西科技大学生命科学与工程学院;陕西科技大学化学与化工学院 |
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| 基金项目： | 山东淄博杰乐宝恩生物科技有限公司科技项目(20124880) |
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| 摘 要： | 本试验在研究酶解猪皮明胶制备抗疲劳肽较适条件和较佳工艺的基础上,通过负重游泳运动建立动物肌肉外周疲劳模型,经过对小白鼠灌胃饲养明胶肽实施营养干预,在检测血乳酸、血尿素氮、肝（肌）糖原含量和运动时间的基础上分析、评价明胶肽抗外周疲劳功效。实验结果证实：和蒸馏水饲养组对比,明胶肽能延长动物运动时间（P〈0.01）,降低疲劳后的血乳酸（P〈0.01）和尿素氮含量（P〈0.01）,提高肝肌糖原（P〈0.01）含量,具有显著的抗疲劳功效,可作为抗疲劳功能食品的添加剂.
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| 关 键 词： | 明胶肽 外周疲劳 抗疲劳作用位点 动物试验 |
The research of the pigskin ploygeline anti-fatigue of peripheral muscle effect |
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| DONG Wen-bin,ZHANG Xiao-qiang,ZHANG Min.The research of the pigskin ploygeline anti-fatigue of peripheral muscle effect[J].Journal of Northwest University of Light Industry,2012(5):77-81. |
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| Authors: | DONG Wen-bin ZHANG Xiao-qiang ZHANG Min |
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| Affiliation: | 1(1.College of Life Science and Engineering,Shaanxi University of Science & Technology,Xi′an 710021,China;2.College of Chemistry and Chemical Engineering,Shaanxi University of Science & Technology,Xi′an 710021,China) |
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| Abstract: | This test according to more suitable conditions and a better process hydrolyze pigskin gelatin preparing anti-fatigue peptide.We establish animal muscle peripheral fatigue model through weight-bearing swimming and feed polygeline to mice implementation of nutrition intervention.In the detection of blood lactate,blood urea nitrogen,liver（muscle） glycogen content and exercise time,we analysis and evaluate gelatin peptide peripheral fatigue effect.Experimental results show： comparing with distilled group,gelatin peptides can be extended to animal movement time（P〈0.01）,reducing the blood lactate（P〈0.01） and urea nitrogen（P〈0.01） after movement,improving the content of the liver（muscle） glycogen（P〈0.01）.This production has significant anti-fatigue effect and can be used as an anti-fatigue food additive. |
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| Keywords: | gelatin peptides peripheral fatigue anti-fatigue action sites animal testing |
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