| 2-甲基-1-(4-甲基苯基)丙酮的合成 |
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| 引用本文： | 孔祥文,张静. 2-甲基-1-(4-甲基苯基)丙酮的合成[J]. 沈阳化工学院学报, 2002, 16(1): 5-7 |
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| 作者姓名： | 孔祥文 张静 |
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| 作者单位： | 沈阳化工学院,辽宁,沈阳,110021 |
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| 基金项目： | ThisprojectwassupportedbytheNaturalScienceFoundationofthecollege(No .0 60 2 15 ) |
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| 摘 要： | 异丁酸与硫酰氯反应得异丁酰氯，适宜的反应条件为：异丁酸滴加温度25－30℃，滴加时间0．5h；反应温度80℃；反应时间1．5h；收率为92％－93％，在催化剂无水三氯化铝存在下，甲苯与异丁酰氯进行酰基化反应得到2－甲基－1－（4－甲基苯基）丙酮，收率为75％，合成产物经红外光普、核磁共振谱鉴定结构正确。
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| 关 键 词： | 甲苯 异丁酰氯 2－甲基－1－（4－甲基苯基） 酰化 合成 异丁酸 亚硫酰氯反应 |
Synthesis of 2-Methyl-1- (4-Methylphenyl) Propanone |
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| Kong Xiangwen,ZHANG Jing. Synthesis of 2-Methyl-1- (4-Methylphenyl) Propanone[J]. Journal of Shenyang Institute of Chemical Technolgy, 2002, 16(1): 5-7 |
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| Authors: | Kong Xiangwen ZHANG Jing |
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| Abstract: | Isobutyryl chloride was synthesized from isobutyric acid and thionyl chloride, the yield was92 % ～93 %. The optimum reaction conditions were dropping temperature 25～30 ℃ ,dropping time0.5 h; reaction temperature 80 ℃, reaction time 1.5 h. Toluene was reacted with isobutyryl chloride inthe presence of aluminum chloride to give 2-methyl-1-(4-methylphenyl)propanone in 75 % yield. IR and1H-NMR spectra showed that the stucture of the product was correct. |
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| Keywords: | methyl 1 (4 methylphenyl)propanone toluene iso butyryl chloride acylation |
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