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Syntheses of trans-5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-oxo-hexahydro-furo[3,2-b]pyrroles (pyrrolidine trans-lactams and trans-lactones): new pharmacophores for elastase inhibition |
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| Authors: | SJ Macdonald DJ Belton DM Buckley JE Spooner MS Anson LA Harrison K Mills RJ Upton MD Dowle RA Smith CR Molloy C Risley |
| Affiliation: | Enzyme Chemistry 2, Development Chemistry 3, Physical Sciences, and Enzyme Pharmacology, GlaxoWellcome Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, U.K. |
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