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Cover Picture: Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI (ChemMedChem 4/2016) |
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| Authors: | Cassie Jarvis Dr. Zhenfu Han Vasilios Kalas Roger Klein Jerome S. Pinkner Dr. Bradley Ford Jana Binkley Dr. Corinne K. Cusumano Dr. Zachary Cusumano Dr. Laurel Mydock‐McGrane Prof. Scott J. Hultgren Prof. James W. Janetka |
| Affiliation: | 1. Washington University School of Medicine, Department of Biochemistry and Molecular Biophysics, St.?Louis, MO, USA;2. Washington University School of Medicine, Department of Molecular Microbiology, St.?Louis, MO, USA;3. Fimbrion Therapeutics Inc., St.?Louis, MO, USA;4. Washington University School of Medicine, Center for Women's Infectious Disease Research (cWIDR), St.?Louis, MO, USA |
| Abstract: | |
| Keywords: | biofilms FimH mannosides urinary tract infections uropathogenic E. coli |