苯胺和碳酸二甲酯合成苯氨基甲酸甲酯的表观动力学与反应机理

以无水醋酸锌为催化剂,研究了碳酸二甲酯(DMC)与苯胺反应合成苯氨基甲酸甲酯(MPC)的表观反应动力学。结果表明:当DMC大量过量时,DMC与苯胺甲氧羰基化一步合成MPC的反应为准一级反应。并通过红外光谱分析了DMC、苯胺与甲醇对醋酸锌催化剂结构的影响,推测了该反应的反应机理。

Apparent kinetics and reaction mechanism of synthesis of methyl phenyl carbamate from aniline and dimethyl carbonate

The apparent kinetics of methyl phenyl carbamate (MPC) synthesis from aniline and dimethyl carbonate (DMC) using anhydrous zinc acetate as a catalyst was studied. The results showed that in the case of substantial excess of DMC, the apparent dynamic model of the one-step synthesis of MPC by methoxycarbonylation of aniline with DMC could be treated as a pseudo first order reaction. The effect of DMC, aniline and methanol on the structure of anhydrous zinc acetate were studied by FT-IR, and the possible mechanism of the reaction of aniline with DMC was speculated.