织纹螺中河豚毒素限量研究

目的提出织纹螺中河豚毒素的限量建议值,为日常监控提供判定依据。方法对织纹螺中河豚毒素的来源、含量情况、毒性、检测标准以及国内外有关河豚毒素、麻痹性贝类毒素的规定等文献资料进行分析比较,探讨织纹螺中河豚毒素的限量要求。结果织纹螺可分为有毒织纹螺、无毒织纹螺、季节性有毒织纹螺,织纹螺中河豚毒素的浓度范围为0～177 mg/kg,而且河豚毒素毒性是麻痹性贝类毒素的30倍以上(以两者对小鼠的经口LD50比较)。对光织纹螺、正织纹螺等常年带毒且毒素含量高的有毒织纹螺应有效识别并禁止采捕、销售、食用,建议无毒织纹螺和季节性有毒织纹螺中河豚毒素的限量为0.05 mg/kg,测定方法采用GB/T 23217—2008《水产品中河豚毒素的测定》。结论提出织纹螺中河豚毒素的限量建议值应合理可行,有效地完善了织纹螺中河豚毒素的监控体系,保障广大公众的身体健康与生命安全。

The limit value of tetrodotoxin in nassariidae

Objective To provide the limit value of tetrodotoxin in nassariidae for the judgment in regular monitoring.Methods In order to investigate the limit value of tetrodotoxin in nassariidae,the source,content,toxicity,testing standards of tetrodotoxin in nassariidae from relevant documents on tetrodotoxins and paralytic shellfish toxins were compared and analyzed.Results According to the toxicity,nassariidae could be divided into toxic,nontoxic,and seasonal toxic types of nassariidae.The concentration of tetrodotoxin in nassariidae was in the range of 0-177mg/kg.The toxicity of tetrodotoxin is 30 times of paralytic shellfish toxin(comparing their LD50 in mice).Toxic nassariidae(for example,Nassarius rutilans,Zeuxis scalaris,etc.) should be recognized and totally banned to be sold and consumed.The limit value of tetrodotoxin in nontoxic nassariidae and seasonal toxic nassariidae was suggested to be 0.05 mg/kg when tested by the standard method GB/T 23217—2008 Determination of tetrodotoxin in aquatic products.Conclusion The suggested limit value of tetrodotoxin in nassariidae should be reasonable and feasible.The system of monitoring tetrodotoxin in nassariidae has been proposed and perfected.