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Ventilation and gas exchange in patients with chronic renal failure treated with hemodialysis (HD) and intermittent peritoneal dialysis (IPD)
Authors:M Wanic-Kossowska
Affiliation:Kliniki Nefrologii Instytutu Chorób Wewnetrznych Akademii Medycznej w Poznaniu.
Abstract:In 18 patients with chronic renal failure treated by hemodialysis (HD) before, during and after dialysis procedure breathing patterns and blood gases were estimated. Significant changes in PdCO2 and PvCO2 during HD may confirm hypothesis that CO2 diffusion into the dialysis fluid play a role in hypoventilation and hypoxemia during HD. PaO2 decrease in patients treated by peritoneal dialysis (PD) after infusion 21 of fluid into the peritoneal cavity. Increase in minute ventilation (VE) and oxygen consumption (ViO2) at 2nd and 4rs hour of PD indicate that substrate metabolism during dialysis relates to alternations in ventilation. In all patients before dialysis treatment presence of ventilation disturbances of restrictive typ were demonstrated with decreased vital capacity (VC), reduced maximal ventilation (MBC) and lower one-second forced expiratory volume (FEV1). Residual volume (RV) was significantly higher. After HD we observed a significant increase of total lung capacity (TLC) and decrease of RV, whereas after PD a significant decrease of RV.
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