| Abstract: | The aqueous solution properties of poly(N-vinyl-2-pyrrolidone) (PVP)-denaturing agents (i.e., thiourea, guanidinium chloride, and carbonate) were studied by viscosity measurements. The polymer dimensions were calculated at 25°C and at previously determined theta temperatures. The unperturbed dimension parameter, K0, hydrodynamic expansion factor, αη, and unperturbed root-mean-square end-to-end distance,  , have been evaluated. Viscosimetrically determined characterisics (e.g., intrinsic viscosity, Huggins constants) and the high values of αη and  can be explained by the interaction between the polymer and denaturing agents. © 1998 John Wiley & Sons, Inc. J Appl Polym Sci 67:1615–1618, 1998 |
