常压下制备乙内酰脲两种方法的比较

利用常压法制备乙内酰脲(海因),产物收率高,纯度好,且具有很好的操作弹性。在常压下分别利用羟基乙腈、氨气和CO2,羟基乙腈和碳酸氢铵为原料,即双气法与碳铵法,分别制备出了海因,并得出了各自的最佳反应条件,其中双气法收率80 3%,碳铵法收率85 8%。双气法制备海因以往未见报道,碳铵法比以往高压制备提高了5个百分点。双气法与碳铵法成本低,收率高,均是工业化生产的好途径。

Methods to prepare hydantoin in normal pressure

High efficient and purification is identified by synthesized hydantoin in normal pressure.Two methods about preparing hydantion in normal pressure were introduced.When ammonium bicarbonate and glycolonitrile were used as raw materials,and the yield of hydantoin is 85.8%.When ammonia and carbon dioxide were used as raw materials,the yield of hydantoin is 80.3%.They are both good methods when they are applied into the practise.