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液体发酵的桑黄多糖对小鼠免疫功能的影响
引用本文:魏静, 陈力, 邓亚君, 邹祥, 徐兴然. 液体发酵的桑黄多糖对小鼠免疫功能的影响[J]. 食品工业科技, 2016, (08): 344-346. DOI: 10.13386/j.issn1002-0306.2016.08.064
作者姓名:魏静  陈力  邓亚君  邹祥  徐兴然
作者单位:1.西南大学药学院
摘    要:研究液体发酵分离纯化得到的桑黄多糖对小鼠免疫功能的影响。研究桑黄多糖对小鼠的免疫器官、碳廓清率以及IL-1、IL-2、IL-4、IL-6、IFN-γ、TNF-α细胞因子的影响,发现桑黄多糖能显著提高小鼠胸腺重量和脾脏重量,增强小鼠碳廓清率,增加IL-2和IFN一γ的含量,降低IL-1、IL-6、TNF-α的含量。证实桑黄多糖能显著增强小鼠的机体免疫力,有一定的抗炎作用。 

关 键 词:液体发酵  桑黄多糖  小鼠  免疫  细胞因子
收稿时间:2015-10-19

Effect of polysaccharides from Phellinus igniarius by liquid fermentation technology on mouse's immunity function
WEI Jing, CHEN Li, DENG Ya-jun, ZOU Xiang, XU Xing-ran. Effect of polysaccharides from Phellinus igniarius by liquid fermentation technology on mouse's immunity function[J]. Science and Technology of Food Industry, 2016, (08): 344-346. DOI: 10.13386/j.issn1002-0306.2016.08.064
Authors:WEI Jing  CHEN Li  DENG Ya-jun  ZOU Xiang  XU Xing-ran
Affiliation:1.College of Pharmaceutical Sciences,Southwest University
Abstract:To study the effect of polysaccharides from Phellinus igniarius by liquid fermetation technology on mouse's immunity function.It mainly studied the immune organs in mice,carbon clearance rate,and IL-1,IL-2,IL-4,IL-6,IFN-γ,TNF-α affected by P. igniarius polysaccharide. The results showed that it could significantly increase the weight of thymus and spleen,enhance carbon clearance rate,increase the content of IL-2 and IFN-γ,reduce the content of IL-1,IL-6 and TNF-α. It was confirmed that polysaccharides from Phellinus igniarius could significantly enhance immunity,and there was a certain anti-inflammatory effects.
Keywords:liquid fermentation technology  polysaccharides from Phellinus igniarius  mice  immune  cytokines
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