| 白果清蛋白对免疫功能低下小鼠的调节作用 |
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| 引用本文： | 邓乾春,段会轲,谢笔钧,唐瑛,黄文.白果清蛋白对免疫功能低下小鼠的调节作用[J].食品科学,2006,27(6):195-199. |
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| 作者姓名： | 邓乾春 段会轲 谢笔钧 唐瑛 黄文 |
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| 作者单位： | 华中农业大学食品科技学院； 广州军区武汉陆军总医院 |
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| 摘 要： | 利用一次造模再次强化的方法观察了白果清蛋白(GinkgoAlbuminProtein,GAP)对环磷酰胺(Cyclophosphamide,CTX)致免疫功能低下模型小鼠的调节作用;实验中观测了脏器指数,体外T、B淋巴细胞增殖能力,NK细胞对肿瘤细胞的杀伤作用,白细胞介素-2(IL-2)的活性,血清中SOD的活性、GSH-Px的活性、MDA含量,骨髓DNA的含量,骨髓有核细胞的数目及小鼠血象等指标;结果表明GAP能增强免疫功能低下模型小鼠的免疫调节能力,刺激模型小鼠造血功能的恢复,并能提高模型小鼠的抗氧化能力。
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| 关 键 词： | 白果清蛋白 免疫功能低下 环磷酰胺 抗氧化活性 免疫调节作用 |
| 文章编号： | 1002-6630（2006）06-0195-05 |
| 收稿时间： | 2005-04-25 |
| 修稿时间： | 2005-04-25 |
Regulating Function of Ginkgo Albumin Protein(GAP) on Immunosuppressive Model in Mice |
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| DENG Qian-chun,DUAN Hui-ke,XIE Bi-jun,TANG Ying,HUANG Wen.Regulating Function of Ginkgo Albumin Protein(GAP) on Immunosuppressive Model in Mice[J].Food Science,2006,27(6):195-199. |
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| Authors: | DENG Qian-chun DUAN Hui-ke XIE Bi-jun TANG Ying HUANG Wen |
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| Affiliation: | 1.Institute of Food Science and Technology, Huangzhong Agricultural University, Wuhan 430070, China; 2.Department of Medical Experiments, Wuhan General Hospital of Guangzhou Military Command, Wuhan 430070, China |
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| Abstract: | The way of one-time-made mode and once more intensification was used in studying the regulating effect of GAP on immunosuppressive model mice induced by Cyclophosphamide (CTX). In the experiments, viscera, T lymphocyte and B lymphocyte proliferation, the cytotoxicity of NK cells, activity of IL-2, SOD activity, GSH-Px activity, MDA content in serum, number of nucleated cells, DNA content in marrow, and blood picture in mice were determined. Results showed that GAP enhances immunoregulation, promotes recuperating of hemopoiesis and increases antioxidative function of model mice. |
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| Keywords: | GAP(ginkgo albumin protein) immunosuppressive cyclophosphamide antioxidative function immunoregulation |
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