| 基于局域表面等离子共振的比色法用于食品质量安全检测的研究进展 |
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| 引用本文： | 韩振宇,孙铁强,刘 颖,宁保安.基于局域表面等离子共振的比色法用于食品质量安全检测的研究进展[J].食品安全质量检测技术,2021,12(14):5568-5576. |
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| 作者姓名： | 韩振宇 孙铁强 刘 颖 宁保安 |
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| 作者单位： | 内蒙古医科大学公共卫生学院 内蒙古 呼和浩特市,军事科学院军事医学研究院环境医学与作业医学研究所 天津 和平区,内蒙古医科大学公共卫生学院,军事科学院军事医学研究院环境医学与作业医学研究所 天津 和平区 |
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| 基金项目： | 国家自然科学基金重大研究计划(no.2018YFC1602904、no.2018YFC1602903)；国家自然科学基金(no . 21976210)。*通讯作者刘颖(1960-),女,博士,教授,研究方向营养与食品安全,E-mailyingruru@sina.com。Fund:This study was financially supported in part by The Major Research Plan of the National Natural Science Foundation of China (No.2018YFC1602904 and 2018YFC1602903) and the National Science Foundation of China (No.21976210).*Corresponding author:LIU Ying,PhD,Professor, Research Interests: Nutrition and Food Safety, E-mail: yingruru@sina.com |
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| 摘 要： | 局域表面等离子体共振(LSPR)是表面等离子共振(SPR)中的一种特殊情况,是光线入射到金属纳米颗粒上引起的共振现象,可被用来实时跟踪生物分子之间在天然状态下的相互作用。这种方法对生物分子无任何损伤,且不需任何标记物。LSPR比色法灵敏度高、多色变化,可用于制作试纸条、试剂盒从而引起人们的广泛关注。本研究解释了LSPR的基本原理以及比色技术的概况,回顾了近5年基于LSPR的比色技术在食品安全方面的应用。最后,对基于LSPR生物传感器比色法的发展和应用以及研究领域所面临的挑战和未来的发展方向进行了讨论。
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| 关 键 词： | 局域表面等离子体共振 生物传感器 比色法 食品安全，检测 |
| 收稿时间： | 2021/3/17 0:00:00 |
| 修稿时间： | 2021/7/14 0:00:00 |
Research progress of colorimetry based on local surface plasmon resonance in food quality and safety detection |
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| HAN Zhen-Yu,SUN Tie-Qiang,LIU Ying,NING Bao-An.Research progress of colorimetry based on local surface plasmon resonance in food quality and safety detection[J].Food Safety and Quality Detection Technology,2021,12(14):5568-5576. |
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| Authors: | HAN Zhen-Yu SUN Tie-Qiang LIU Ying NING Bao-An |
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| Affiliation: | Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment & Food Safety, Tianjin Institute of Environmental and Operational Medicine,Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment & Food Safety, Tianjin Institute of Environmental and Operational Medicine,Inner Mongolia Medical University,Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment & Food Safety, Tianjin Institute of Environmental and Operational Medicine |
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| Abstract: | Local surface plasmon resonance (LSPR) is a special case of surface plasmon resonance (SPR), which is the resonance phenomenon caused by the incident light rays on metal nanoparticles.It can be used to track the interactions between biomolecules in real time in their natural state.This method has no damage to biomolecules and does not require any markers.The colorimetric method based on LSPR biosensor has many advantages, such as high sensitivity, multi-color change, and can be used to make test strips and kits.In this review, we explain the basic principles of LSPR and the overview of colorimetric technology, and review the application of LSPR-based colorimetric technology in food safety in the last 5 years.Finally, we discuss the development and application of LSPR-based biosensor colorimetry, the challenges and future directions in this field. |
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| Keywords: | local surface plasmon resonance biosensor colorimetric food safety testing |
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