Green synthesis,characterisation and biological studies of AgNPs prepared using Shivlingi (Bryonia laciniosa) seed extract |
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| Authors: | Acharya Balkrishna Niti Sharma Vinay Kumar Sharma Nayan Deep Mishra Chandra Shekhar Joshi |
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| Affiliation: | 1. Drug Discovery & Development Division, Patanjali Research Foundation, Haridwar Uttarakhand, India ; 2. University of Patanjali, Haridwar Uttarakhand, India |
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| Abstract: | Green synthesis of silver nanoparticles (AgNPs) using Shivlingi (Bryonia laciniosa) seed extract was carried out. Characterisation of synthesised nanoparticles was accomplished through the optical absorption and photoluminescence spectrum, X‐ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy. The XRD analysis further confirmed the size of nanoparticles ∼15 nm. TEM images revealed homogeneous spherical ∼10 nm Bryonia extract capped AgNPs. The biological studies indicated that both Bryonia seed extract and the nanoparticles lack anti‐microbial activity; however, the nanoparticles had better cytotoxicity and total antioxidant activity. The Lethal concentration (LC)50 value of water extract and the nanoparticles were found to be 1091 and 592 μg/ml, respectively. The lower LC50 of nanoparticles indicates that it is more cytotoxic than the crude extract. The results indicate that the Bryonia seed is safe to be used as a medicine and the formation of their nanoparticle has further enriched the chemical reactivity, energy absorption and biological mobility.Inspec keywords: silver, nanoparticles, nanomedicine, particle size, microorganisms, cellular biophysics, nanofabrication, photoluminescence, X‐ray diffraction, transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectra, Raman spectra, antibacterial activity, biochemistryOther keywords: green synthesis, biological studies, Shivlingi seed extraction, Bryonia laciniosa, silver nanoparticles, optical absorption, photoluminescence spectrum, X‐ray diffraction, transmission electron microscopy, scanning electron microscopy, SEM, Fourier transform infrared spectroscopy, Raman spectroscopy, XRD analysis, nanoparticle size, TEM images, homogeneous spherical images, antioxidant activity, water extraction, chemical reactivity, energy absorption, biological mobility, Ag |
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