Surface‐functionalised hybrid nanoparticles for targeted treatment of cancer |
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| Authors: | Hasnat Tariq Syed Ali Imran Bokhari |
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| Affiliation: | 1. Department of Biotechnology, Quaid‐i‐Azam University, Islamabad Pakistan ; 2. Department of Biological Sciences, International Islamic University, Islamabad Pakistan |
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| Abstract: | Cancer is a leading cause of death worldwide. Despite the great advancement in understanding the pharmacology and biology of cancer, it still signifies one of the most serious human‐health related problems. The current treatments for cancer may include surgery, radiotherapy, and chemotherapy, but these procedures have several limitations. Current studies have shown that nanoparticles (NPs) can be used as a novel strategy for cancer treatment. Developing nanosystems that allow lower doses of therapeutic agents, as well as their selective release in tumour cells, may resolve the challenges of targeted cancer therapy. In this review, the authors discuss the role of the size, shape, and surface modifications of NPs in cancer treatment. They also address the challenges associated with cancer therapies based on NPs. The overall purpose of this review is to summarise the recent developments in designing different hybrid NPs with promising therapeutic properties for different types of cancer.Inspec keywords: tumours, reviews, patient treatment, nanomedicine, surgery, radiation therapy, cellular biophysics, nanobiotechnology, nanoparticles, cancerOther keywords: current treatments, cancer treatment, targeted cancer therapy, cancer therapies, surface‐functionalised hybrid nanoparticles, targeted treatment, serious human‐health related problems |
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