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Efficient Synthesis of β,γ‐Alkynyl α‐Amino Acid Derivatives by Ag(I)‐Catalyzed Alkynylation of α‐Imino Esters |
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| Authors: | Jian‐Xin Ji Terry&#x;T‐L Au‐Yeung Jing Wu Chiu&#x;Wing Yip Albert&#x;S&#x;C Chan |
| Abstract: | The first catalytic synthesis of β,γ‐alkynyl α‐amino acid derivatives was achieved by direct addition of terminal alkynes to α‐imino esters in the presence of an Ag(I) salt under mild reaction conditions. |
| Keywords: | alkynes α ‐amino acids α ‐imino ester catalytic synthesis silver(I) salt |