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生物工程中自动化显微注射技术研究进展
引用本文:田桂中,陈涛,王淑妍,刘志强.生物工程中自动化显微注射技术研究进展[J].微纳电子技术,2011,48(8):536-542.
作者姓名:田桂中  陈涛  王淑妍  刘志强
作者单位:1. 江苏科技大学机械工程学院,江苏镇江,212003
2. 中华人民共和国镇江出入境检验检疫局,江苏 镇江,212008
基金项目:国家自然科学基金资助项目,江苏科技大学人才引进基金资助项目
摘    要:阐述了现有显微注射系统的结构组成与功能特征,介绍了自动化显微注射技术的国内外研究现状。分析了显微注射中各项自动化操作研究的技术组成及其优缺点,涉及图像处理、微机械加工、智能材料、自动控制、气动、激光与计算机等技术或方法。指出了研究基于手工细胞注射技术路线的全自动显微注射技术的关键问题和困难。展望了自动化显微注射技术的发展方向,并从三方面简要介绍了各方向的研究进展,包括自动化显微注射系统结构、微注射针进针机构和基于仿生微通道的微注射量精确控制技术。

关 键 词:生物工程  细胞工程  显微注射  显微操作  自动化

Research Progress on Auto-Microinjection Technology in Bio-Engineering
Tian Guizhong,Chen Tao,Wang Shuyan,Liu Zhiqiang.Research Progress on Auto-Microinjection Technology in Bio-Engineering[J].Micronanoelectronic Technology,2011,48(8):536-542.
Authors:Tian Guizhong  Chen Tao  Wang Shuyan  Liu Zhiqiang
Affiliation:1(1.School of Mechanical Engineering,Jiangsu University of Science & Technology,Zhenjiang 212003,China;2.Zhenjiang Entry-Exit Inspection and Quarantine of the State Administration,Zhenjiang 212008,China)
Abstract:The structure components and function features of the existing microinjection system are expatiated,and the oversea and home research status of the automatic microinjection techno-logy is summarized.With the technologies of the image process,micro machine manufacture,smart material,automatic control,pneumatic,laser and computer,and other methods,the technology components,merits and demerits of the auto manipulation in microinjection are analyzed in detail.The key issues and difficulties of the full automatic microinjection technology based on the manual cell injection technology are pointed out.The development direction of the automatic microinjection technology is briefly presented,the research progress is introduced from three aspects,i.e.the automatic microinjection system,needle inserting system of the microinjection needle and microinjection precision control technology based on the biomimetic micro-channel.
Keywords:bio-engineering  cell engineering  microinjection  micro-manipulation  automation
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