Antimicrobial Activity of Monoacyl Hexose Coexistent with Lysozyme against Gram-Positive Bacilli |
| |
| Authors: | Yoshiyuki Watanabe Yuko Shirai Masaki Miyake Junya Kitano Shuji Adachi |
| |
| Affiliation: | 1. Department of Biotechnology and Chemistry , Faculty of Engineering, Kinki University , Higashihiroshima , Japan wysyk@hiro.kindai.ac.jp;3. Department of Biotechnology and Chemistry , Faculty of Engineering, Kinki University , Higashihiroshima , Japan;4. Division of Food Science and Biotechnology , Graduate School of Agriculture, Kyoto University , Sakyo-ku , Kyoto , Japan |
| |
| Abstract: | The antimicrobial activities of myristoyl, palmitoyl, or stearoyl hexoses, which were glucose, mannose, and galactose, coexistent with lysozyme against three Gram-positive bacteria, Bacillus coagulans, Bacillus subtilis, and Bacillus licheniformis, were measured in order to investigate the availability of monoacyl hexose as an antimicrobial co-agent. The lysozyme exhibited an antimicrobial activity against Bacillus subtilis and Bacillus licheniformis, but there was no significant difference between the dependencies of the antimicrobial activity against the two bacteria on the lysozyme concentration. However, the antimicrobial activities of the monoacyl hexoses coexistent with the lysozyme were different between those against the two bacteria. The stearoyl hexose coexistent with the lysozyme exhibited the highest antimicrobial activity against two bacteria. It was indicated that the antimicrobial action of the monoacyl hexose would be exerted parallel with the bacterial lysis of lysozyme. Stearoyl hexose, which has a high hydrophobicity, coexistent with the lysozyme could exhibit a higher antimicrobial activity than only the lysozyme. |
| |
| Keywords: | Antimicrobial activity Enzymatic synthesis Gram-positive bacteria Lysozyme Monoacyl hexose |
|
|
