An elastic computerized brain atlas for the analysis of clinical PET/SPET data |
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Authors: | G Rizzo MC Gilardi A Prinster F Grassi G Scotti S Cerutti F Fazio |
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Affiliation: | Department of Nuclear Medicine Scientific Institute H San Raffaele, INB-CNR, University of Milan, Italy. |
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Abstract: | An elastic computerized brain atlas was developed for the analysis of positron emission tomography/single-photon emission tomography (PET/SPET) data. It consists of a set of digital anatomical contours and a template of regions of interest, schematically describing the brain, derived from a currently used anatomical/functional brain atlas. A warping algorithm, matching equivalent contours, was implemented to elastically fit the atlas to individual brain images. The elastic computerized brain atlas was applied to representative magnetic resonance imaging (MRI)-PET/SPET studies, MRI providing the anatomical information used by the matching procedure. The atlas is suited for clinical use in a nuclear medicine environment. |
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