(1) School of Materials, University of Manchester, Grosvenor Street, Manchester, M1 7HS;(2) Department of Oral Biology, University of Leeds, Clarendon Way, LS2 9LU
Abstract:
A number of bioactive ceramics have been researched since the development of Bioglass in the 1970s. Fluorapatite mullite has been developed from the dental glass-ceramics used for more general hard tissue replacement. Being brittle in nature, glass-ceramics are currently used mainly as coatings. This paper shows that fluorapatite glass LG112 can be used as a sputtered glass coating on roughened surfaces of Ti6Al4V for possible future use for medical implants. An AFM was used to measure the roughness of the surface before and after coating to determine the change in the topography due to the coating process as this greatly affects cell attachment. The sputter coating partially filled in the artificially roughened surface, changing the prepared topography. Osteoblasts have been successfully grown on the surface of these coatings, showing biocompatibility with bone tissue and therefore potential use in hard tissue repair.
s. Fluorapatite mullite has been developed from the dental glass-ceramics used for more general hard tissue replacement. Being brittle in nature, glass-ceramics are currently used mainly as coatings. This paper shows that fluorapatite glass LG112 can be used as a sputtered glass coating on roughened surfaces of Ti6Al4V for possible future use for medical implants. An AFM was used to measure the roughness of the surface before and after coating to determine the change in the topography due to the coating process as this greatly affects cell attachment. The sputter coating partially filled in the artificially roughened surface, changing the prepared topography. Osteoblasts have been successfully grown on the surface of these coatings, showing biocompatibility with bone tissue and therefore potential use in hard tissue repair.