| 2-氯-N-苯基苯甲酰胺的合成及其抑菌活性研究 |
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| 引用本文： | 罗青春,田珈源,刘森,刘涵,陈志伟,向文良. 2-氯-N-苯基苯甲酰胺的合成及其抑菌活性研究[J]. 西华大学学报(自然科学版), 2011, 30(6): 85-88 |
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| 作者姓名： | 罗青春 田珈源 刘森 刘涵 陈志伟 向文良 |
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| 作者单位： | 1. 西华大学生物工程学院,四川成都,610039
2. 西华大学物理与化学学院,四川成都,610039 |
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| 基金项目： | 四川省食品生物技术重点实验室开放基金(SZJJ2009-014) |
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| 摘 要： | 目的:合成2-氯-N-苯基苯甲酰胺,并测定其对水稻纹枯病菌(Rhizoctonia solani)和油菜菌核病菌(Scle-rotiua sclerotiorum)的抑菌活性。方法:以2-氯苯甲酰氯和苯胺为原料,采用酰卤的胺解法合成2-氯-N-苯基苯甲酰胺,并通过IR,1H NMR进行结构确认。以多菌灵为对照,采用平板生长速率法测定其对水稻纹枯病菌和油菜菌核病菌菌丝的抑制率。结果:2-氯-N-苯基苯甲酰胺对水稻纹枯病菌和油菜菌核病菌均有较好的抑菌活性,其抑制中浓度IC50分别为5.00,6.38 mg/L。结论:合成的2-氯-N-苯基苯甲酰胺为研究和开发高效、低毒、对非靶标生物安全的新型植物病原真菌农药奠定了较好基础。
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| 关 键 词： | 2-氯-N-苯基苯甲酰胺 抑菌活性 水稻纹枯病菌 油菜菌核病菌 |
Synthesis of 2-Chloro-N-phenylbenzamide and Research on Its Antifungal Activity |
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| LUO Qing-chun,TIAN Jia-yuan,LIU Sen,LIU Han,CHEN Zhi-wei,XIANG Wen-liang. Synthesis of 2-Chloro-N-phenylbenzamide and Research on Its Antifungal Activity[J]. Journal of Xihua University(Natural Science Edition), 2011, 30(6): 85-88 |
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| Authors: | LUO Qing-chun TIAN Jia-yuan LIU Sen LIU Han CHEN Zhi-wei XIANG Wen-liang |
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| Affiliation: | LUO Qing-chun1,TIAN Jia-yuan2,LIU Sen1,LIU Han1,CHEN Zhi-wei1,XIANG Wen-liang1(1.School of Bioengineering,Xihua University,Chengdu 610039 China,2.School of Physics and Chemistry,Chengdu 610039 China) |
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| Abstract: | In order to synthesize 2-chloro-N-phenylbenzamide and evaluate its antifugal activity against Rhizoctonia solani and Sclerotiua sclerotiorum,2-Chloro-N-phenylbenzamide was synthesized with 2-chloro-benzoyl chloride and aniline by acyl halide aminolysis reaction.Its structure was confirmed by IR and 1HNMR.The plate growth rate method was used to test its inhibition rate of growth against R.solani and S.sclerotiorum using carbendazim as comparison.2-Chloro-N-phenylbenzamide showed good inhibitory effect on my... |
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| Keywords: | 2-Chloro-N-phenylbenzamide antifungal activity rhizoctonia solani sclerotiua |
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