Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a four-week study in cynomolgus monkeys |
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| Authors: | SP Henry H Bolte C Auletta DJ Kornbrust |
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| Affiliation: | The Sports Medicine and Shoulder Service, The Hospital for Special Surgery, Cornell University Medical College, New York, New York, USA. |
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| Abstract: | Partial-thickness rotator cuff tears are now acknowledged to be an important entity in the spectrum of the impingement syndrome. The pathogenesis of partial-thickness tears is often age- and activity-related. Surgical decision making is influenced by the extent of the tear and the associated bony and soft-tissue pathology. |
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