大豆黄酮对机体疲劳应激下抗氧化能力的影响

以26名健康大学生志愿者为受试对象，采用逐级递增负荷疲劳运动方式，研究大豆黄酮对机体疲劳应激下抗氧化能力的影响。结果显示，疲劳运动后人体血清CAT、SOD酶活性有所增加，而GSH-Px酶活性显著升高（p〈0．05），血清MDA含量有所升高；服用大豆黄酮后进行疲劳应激，三种抗氧化酶活性均升高，且均稍高于对照组应激后水平，其中GSH-Px活性显著高于服用前（p〈0．05），SOD活性极显著高于服用前（p〈0．01），显著高于服用后（p〈0．05），MDA含量几乎没有较多变化，且与对照组应激后水平相比有所降低。结果表明，大豆黄酮能明显增强应激机体的抗氧化能力，减少应激机体的自由基产生，具有一定的抗应激效应。

Effect of Daidzein on Anti-oxidative Ability of Body under Fatigue-Stress

26 healthy volunteer undergraduates were selected to observe the anti-oxidative effect of daidzein under fatigue-stress, with the method of the gradual-loading-exercise. The results showed that, after exercising, the activities of CAT, GSH-Px, SOD and the content of MDA in the control group increased, and the change of the activity of GSH-Px was significant (p<0.05). In the daidzein group, the activities of three kinds of anti-oxidases all increased after exercising, and were higher than those of the control group. The activities of GSH-Px and SOD after exercising increased significantly compared with those before taking daidzein (p<0.05 or p<0.01) and the activity of SOD increased significantly compared with that after taking daidzein (p< 0.05). The content of MDA of the daidzein group increased little after exercising, and was lower than that of the control group. These results indicated that daidzein could improve the anti-oxidative ability and reduce the level of MDA under fatigue-stress and thus enhance the anti-stress ability.