A probabilistic simulator for population dynamics of quasispecies |
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| Authors: | Masayuki Fujisawa Yoshiteru Ishida |
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| Affiliation: | (1) Department of Knowledge-Based Information Engineering, Toyohashi University of Technology, Toyohashi, Japan;(2) Department of Knowledge-Based Information Engineering, Toyohashi University of Technology, Tempaku, Toyohashi 441-8580, Japan |
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| Abstract: | We constructed a probabilistic simulator that allows all the events in population dynamics such as death, birth, mutation,
and suppression/stimulation to be described by probabilistic rules. The simulator also facilitates a lattice used for expressing
distribution and diversity (number of distinct strains) of quasispecies. The simulator is used to investigate the diversity
threshold in HIV and T-cell interaction.
This work was presented in part at the 13th International Symposium on Artificial Life and Robotics, Oita, Japan, January
31–February 2, 2008 |
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| Keywords: | Probabilistic simulation Population dynamics Lattice model Diversity threshold Mutation |
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