可降解生物医用Zn-1Al合金的制备及性能研究

以商业铸态纯锌和纯铝为原料,制备得到Zn-1Al铸态合金。利用光学显微镜和扫描电子显微镜观察Zn-1Al铸态合金的显微组织,利用万能试验机测定Zn-1Al铸态合金的压缩力学性能,利用模拟体液浸泡实验表征Zn-1Al铸态合金的生物降解性能和诱导Ca-P沉积能力。结果表明,向Zn中加入1%(质量分数)的合金元素Al后,铸态纯锌的显微组织明显细化,且Zn-1Al合金的压缩力学性能也较铸态纯锌明显提高。模拟体液浸泡实验结果表明铸态Zn-1Al合金在浸泡过程中降解速率与铸态纯锌相比未出现明显差别,但Zn-1Al合金能更有效地诱导Ca-P沉积。

Fabrication and Investigation on Properties of Degradable Zn-1AlAlloy for Biomedical Applications

As-cast Zn-1 Al alloy was fabricated with commercially pure zinc and pure aluminum as raw materials.Microstruc-ture of the as-cast Zn-1 Al alloy was observed by optical microscopy and scanning electron microscopy,and the compressive mechani-cal properties were measured by a universal test machine.The biodegradable property and the ability to induce Ca-P precipitation of the as-cast Zn-1 Al alloy were characterized by immersion tests in simulated body fluid.The results show that the microstructures of the as-cast Zn-1Al alloy were obviously refined by adding 1wt% Al element.In addition,the compressive mechanical properties of the as-cast Zn-1 Al alloy were also enhanced compared with that of as-cast pure zinc.The immersion tests in simulated body fluid suggest that the as-cast Zn-1Al alloy has a similar degradable rate compared to as-cast pure Zn.However,Zn-1Al alloy can more efficiently induce Ca-P precipitation during immersion tests.