1,2:5,6-二-O-异亚丙基-D-甘露醇合成工艺及应用

1,2:5,6-二-O-异亚丙基-D-甘露醇是合成具有重要生理活性天然产物的一种重要手性合成子。文中概述了1,2:5,6-二-O-异亚丙基-D-甘露醇国内外合成及应用、市场概况,重点介绍目前开发新合成工艺的进展及其特点。该新工艺具有原料来源丰富、反应时间短、工艺条件温和及易于实现工业化生产的特点。

Synthesis Process and Application of 1,2:5,6-di-O-isopropylidene-D-mannitol

1, 2:5, 6-di-O-isopropylidene-D-mannitol is a major chiral synthpon for the synthesis of natural substances with important physiological activities. The article gives general descriptions of the synthesis and application and market situation at home and abroad and specially introduces the progress of the new synthesis processes currently being developed and their features. The new process is characterized available rich raw material resources, short reaction time, mild process conditions and easy realization of commercial production.