| 芳基-α-氯代-α-羰基肟的合成研究 |
| |
| 引用本文： | 龚亚红,姬文娟,连昕,王宇光,朱冰春.芳基-α-氯代-α-羰基肟的合成研究[J].精细化工中间体,2013(4):11-13,38. |
| |
| 作者姓名： | 龚亚红 姬文娟 连昕 王宇光 朱冰春 |
| |
| 作者单位： | [1]浙江工业大学生环学院,浙江杭州310014 [2]浙江省化工研究院,浙江杭州310023 |
| |
| 基金项目： | 国家自然科学基金项目（21202151）; “十二五”国家科技支撑计划项目（2011BAE06B01-20）; 浙江省重点科技创新团队项目（2010R50018） |
| |
| 摘 要： | 以芳基乙酮为原料,亚硝酸异戊酯做亚硝化试剂,通入氯化氢气体,合成了9个α-氯代-α-羰基肟类化合物。反应时间可由传统方法的56 h缩短至26 h缩短至23 h,目标产物收率由30%提高至80%。化合物结构经1H NMR和IR确认。
|
| 关 键 词： | α-氯代-α-羰基肟 合成 结构表征 异噁唑啉 |
Study on the Synthesis of a-Chloro-a-carbonyl Oxime |
| |
| GONG Ya-hon,JI Wen-juan,LIAN Xin,WANG Yu-guan,ZHU Bing-chun.Study on the Synthesis of a-Chloro-a-carbonyl Oxime[J].Fine Chemical Intermediates,2013(4):11-13,38. |
| |
| Authors: | GONG Ya-hon JI Wen-juan LIAN Xin WANG Yu-guan ZHU Bing-chun |
| |
| Affiliation: | . ( 1. College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310014, China; 2. Zhejiang Chemical Industry Research Institute, Hangzhou 310023, China) |
| |
| Abstract: | Nine novel a-chloro-a-carbonyl oximes were synthesized starting from acetophenone, isoamyl nitrite and anhydrous hydrogen chloride. Comparing with conventional method, this route can reduce the reaction time from 5~6 hours to 2-3 hours, and increase the yield of the target products from 30% to 80%. The structures of the compounds were confirmed by IH NMR and IR spectra. Key words： a-chloro-a-carbonyl oxime ; synthesis ; characterization ; isoxazoline |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
