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Streptococcus zooepidemicus H23生产透明质酸营养条件的优化
引用本文:刘立明,堵国成,李寅,陈坚.Streptococcus zooepidemicus H23生产透明质酸营养条件的优化[J].食品与发酵工业,2003,29(6):31-34.
作者姓名:刘立明  堵国成  李寅  陈坚
作者单位:1. 江南大学生物工程学院环境生物技术室,无锡,214036;江南大学工业微生物教育部重点实验室,无锡,214036
2. 江南大学生物工程学院环境生物技术室,无锡,214036
3. 江南大学工业微生物教育部重点实验室,无锡,214036
摘    要:在发酵罐水平上研究了酵母粉用量、初糖浓度和碳氮比以及补加葡萄糖对Strepto coccuszoopeidemicusH2 3发酵生产透明质酸的影响。利用上述条件在 5L罐上进行发酵实验 ,16h时发酵液中透明质酸质量浓度为 4 83g/L。

关 键 词:透明质酸  Streptococcus  zooepidemicus  营养条件优化  碳氮比
修稿时间:2002年7月2日

Optimization of Nutritional Conditions on the Production of Hyaluronic Acid by Streptococcus zooepidemicus H23
Liu Liming , Du Guocheng Li Yin , Chen Jian.Optimization of Nutritional Conditions on the Production of Hyaluronic Acid by Streptococcus zooepidemicus H23[J].Food and Fermentation Industries,2003,29(6):31-34.
Authors:Liu Liming  Du Guocheng Li Yin  Chen Jian
Affiliation:Liu Liming 1,2 Du Guocheng 1 Li Yin 1,2 Chen Jian 2 1
Abstract:The effects of some nutritional conditions,such as yeast extract concentration,feeding glucose as well as ratio of C/N in batch culture,on the production of hyaluronic acid by Streptococcus zooepidemicus H23 were investigated In 5 L jar fermentor batch culture:(1)more than 20*#g/L of yeast extract inhibited the accumulation of HA;(2)production of HA was increased from 4 338*#g/L to 4 837g/L by simply feeding glucose;(3)increasing the concentration of glucose and yeast extract proportionally with constant C/N ratio(12∶1) improved the production of HA It was also found that,glucose consumption and HA production almost stopped under the condition of nitrogen difficiency
Keywords:Streptococcus  zooepidemicus  hyaluronic acid  ratio of C∶N  nutritional conditions
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