The nutraceutical value of grain legumes: characterisation of bioactives and antinutritionals related to diabesity management |
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Authors: | Sara Bosi Valeria Bregola Giovanni Dinelli Grazia Trebbi Francesca Truzzi Ilaria Marotti |
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Affiliation: | Department of Agricultural and Food Science, University of Bologna, viale Fanin 44, Bologna, 40127 Italy |
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Abstract: | Beyond the nutritional value, legumes and particularly common beans are found in several dietary supplements used to treat diabesity (diabetes and obesity). These products contain not only inhibitors of carbohydrate-hydrolising enzymes (α-amylase, α-glucosidase), but also antinutritional factors that can cause adverse effects on human health. In the present research, twenty-two accessions of grain legumes were screened for bioactive (α-amylase and α-glucosidase inhibitors) and antinutritional (lectins, flatulence-producing sugars, trypsin inhibitors) phytochemicals. Results showed that four accessions had high α-amylase inhibiting activities (AI > 30%), and particularly the common bean ‘Great Northern’ resulted of interest for its high carbo-blocker activity (AI = 42.6 ± 0.5%), absence of lectins, low amounts of flatulence-producing oligosaccharides (2.5 ± 0.2 g/100 g DW) and low anti-trypsin activity (22.5 ± 4.3 trypsin inhibiting unit/mg DW). The knowledge offered from this work provides leads to the ultimate goal of developing new, more effective and safer dietary supplements for diabesity management. |
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Keywords: | Bioactives diabesity dietary supplements legumes polyphenols α-amylase inhibitors α-glucosidase inhibitors |
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