| 一锅法合成溴代甲苯及1-溴丙烷的研究 |
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| 引用本文： | 张书文,柏雷,侯林艳,潘玉莲,陈贺. 一锅法合成溴代甲苯及1-溴丙烷的研究[J]. 化学世界, 2011, 52(9): 538-540,546 |
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| 作者姓名： | 张书文 柏雷 侯林艳 潘玉莲 陈贺 |
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| 作者单位： | 河北大学化学与环境科学学院,河北保定,071002 |
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| 摘 要： | 以水为溶剂,以甲苯、1-丙醇和溴为原料,采用“一锅法”在合成对溴甲苯和邻溴甲苯的同时利用甲苯溴代生成的溴化氢进一步合成了1-溴丙烷.通过实验优化并确定了反应条件,其最佳工艺条件为:反应物的摩尔比为n(甲笨):n(溴)∶n(醇)=1∶1∶0.8；甲苯溴代阶段的反应温度为20～25℃;反应时间为2.5h;对溴甲苯和邻溴甲苯...
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| 关 键 词： | 一锅法 对溴甲苯 邻溴甲苯 1-溴丙烷 原子经济性 环境友好 |
Study on Synthesis of Bromotoluene and 1-Bromopropane by One-pot Method |
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| ZHANG Shu-wen,BAI Xue,HOU Lin-yan,PAN Yu-lian,CHEN He. Study on Synthesis of Bromotoluene and 1-Bromopropane by One-pot Method[J]. Chemical World, 2011, 52(9): 538-540,546 |
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| Authors: | ZHANG Shu-wen BAI Xue HOU Lin-yan PAN Yu-lian CHEN He |
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| Affiliation: | ZHANG Shu-wen,BAI Xue,HOU Lin-yan,PAN Yu-lian,CHEN He(College of Chemistry and Environment Science,Hebei University,Hebei Baoding 071002,China) |
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| Abstract: | p-Bromotoluene and o-bromotoluene were synthesized by one-pot reaction using water as solvent and toluene,1-propanol and bromine as raw material.Meanwhile,the hydrogen bromide,generated by bromination of toluene was used to synthesize 1-bromopropane.Through optimizing,the optimum reaction conditions were the mol ratio of toluene:Br2:1-propanol was 1∶1∶0.8,and the reaction was carried out at 20~25 °C for 2.5 h.Under the optimum conditions,the yield of p-bromotoluene and o-bromotoluene were 66.4% and 24.7%,respectively.The yield of 1-bromopropane was up to 80% after refluxing for 1.5 h in 1-propanol.The atom utilization of the process reached almost 100%,which significantly reduced costs and improved the economic efficiency. |
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| Keywords: | one-pot method p-bromotoluene o-bromotoluene 1-bromopropane atom economy |
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