| pH值对克雷伯氏肺炎杆菌发酵甘油产1,3-丙二醇的影响与控制 |
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| 引用本文： | 徐卫涛,钟志辉,付水林,宫衡. pH值对克雷伯氏肺炎杆菌发酵甘油产1,3-丙二醇的影响与控制[J]. 化学与生物工程, 2011, 28(8): 81-83. DOI: 10.3969/j.issn.1672-5425.2011.08.022 |
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| 作者姓名： | 徐卫涛 钟志辉 付水林 宫衡 |
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| 作者单位： | 华东理工大学生物反应器工程国家重点实验室,上海,200237 |
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| 摘 要： | 在克雷伯氏肺炎杆菌发酵甘油产1,3-丙二醇(1,3-PD)的过程中,不同的pH值控制对菌体生长、产物和副产物的生成有着重要的影响.通过对发酵过程中不同pH值控制下的代谢分析,发现pH值较低时菌体生长较慢,有利于副产物2,3-丁二醇的生成;pH值较高时菌体生长较快,有利于副产物乳酸的生成.通过两阶段pH值控制策略,即在发...
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| 关 键 词： | 1,3-丙二醇 甘油 克雷伯氏肺炎杆菌 pH值控制 |
Research of Influence of pH Value on the Fermentation of Glycerol to 1,3-Propanediol by Klebsiella Pneumoniae |
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| XU Wei-tao,ZHONG Zhi-hui,FU Shui-lin,GONG Heng. Research of Influence of pH Value on the Fermentation of Glycerol to 1,3-Propanediol by Klebsiella Pneumoniae[J]. Chemistry & Bioengineering, 2011, 28(8): 81-83. DOI: 10.3969/j.issn.1672-5425.2011.08.022 |
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| Authors: | XU Wei-tao ZHONG Zhi-hui FU Shui-lin GONG Heng |
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| Affiliation: | XU Wei-tao,ZHONG Zhi-hui,FU Shui-lin,GONG Heng(State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology,Shanghai 200237,China) |
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| Abstract: | During the fermentation of glycerol to 1,3-propanediol(1,3-PD)by Klebsiella pneumoniae,different pH value control strategy had a significant impact on cell growth and the biosynthesis of products and by-products.Through the metabolic analysis of fermentation process under different pH value controls,it was found that the cell growth rate was slow,the yield of 2,3-butanediol increased under low pH value;the cell growth rate was high,the yield of lactate increased under high pH value.By two-stage control of p... |
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| Keywords: | 1 3-propanediol glycerol Klebsiella pneumoniae pH value control |
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